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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23B
All Species:
45.15
Human Site:
Y605
Identified Species:
82.78
UniProt:
Q15437
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15437
NP_006354.2
767
86479
Y605
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Q
Chimpanzee
Pan troglodytes
XP_001140754
767
86435
Y605
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Q
Rhesus Macaque
Macaca mulatta
XP_001091771
765
86128
Y603
S
P
D
E
S
S
Y
Y
R
H
H
F
M
R
Q
Dog
Lupus familis
XP_534332
767
86392
Y605
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D662
767
86419
Y605
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513018
765
86087
Y603
S
P
D
E
S
S
Y
Y
R
H
H
F
M
R
Q
Chicken
Gallus gallus
Q5ZK03
767
86285
Y605
S
P
D
E
S
S
Y
Y
R
H
H
F
A
R
Q
Frog
Xenopus laevis
NP_001086405
741
83183
R585
Y
Y
R
H
H
F
A
R
Q
D
L
T
Q
S
L
Zebra Danio
Brachydanio rerio
Q7SZE5
765
86062
Y603
S
P
D
E
S
T
Y
Y
R
H
Q
F
M
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392515
768
85881
Y606
S
P
D
E
T
S
F
Y
R
H
M
L
M
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780042
764
86244
Y604
S
P
D
E
T
S
F
Y
R
H
M
L
I
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15303
768
85366
Y609
S
P
D
E
T
A
F
Y
R
H
I
F
T
R
E
Red Bread Mold
Neurospora crassa
Q9C284
775
86260
Y608
S
P
D
E
T
A
F
Y
R
H
V
L
N
H
E
Conservation
Percent
Protein Identity:
100
99.4
84.7
97.6
N.A.
97.1
N.A.
N.A.
84.7
93
88.6
85.5
N.A.
N.A.
73.5
N.A.
75.8
Protein Similarity:
100
99.6
92.5
98.9
N.A.
98.5
N.A.
N.A.
92.4
96.6
92.1
91.6
N.A.
N.A.
85.4
N.A.
85.6
P-Site Identity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
93.3
100
0
80
N.A.
N.A.
60
N.A.
60
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
93.3
100
6.6
86.6
N.A.
N.A.
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51
57.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.2
71.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
8
0
0
0
0
0
39
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
93
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
31
% E
% Phe:
0
0
0
0
0
8
31
0
0
0
0
70
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
93
54
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
24
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
31
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
0
8
0
62
% Q
% Arg:
0
0
8
0
0
0
0
8
93
0
0
0
0
85
0
% R
% Ser:
93
0
0
0
62
70
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
31
8
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
62
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _